Welcome to the TMCrys server!

Given the amino acid sequence of a transmembrane protein, TMCrys predicts the probability of its successful solubilization, purification and crystallization as well as the success for all these three steps together. The prediction is based on an XGBoost Decision Tree algorithm and data from PDBTM database and TargetTrack experiments.

You can find more information of the method in the Manual. Links to the paper of the method and the server can be found in the About section.

You can submit protein sequences here.

An example output can be found here.